01. What is CBD?
CBD is a Pleiotropic compound (produces many effects through molecular pathways). CBD (CannaBiDiol) is extracted from an organic plant known as Hemp, part of the cannabis family. It is a type of cannabinoid that links up with the Endocannabinoid system – a system that you naturally have within your body.
Experts believe CBD works in three primary ways.
Through the endocannabinoid system – The first is through the endocannabinoid system (ECS), which is composed of:
Receptors – There are CB1, found in the Central Nervous System (CNS) and CB2 receptors, found in the peripheral nervous system in the ECS. They exist throughout the body and are the compounds to which endocannabinoids (like CBD) bind.
Enzymes – The enzymes appear in many forms. However, only two types of enzymes in the ECS can break down CBD and other endocannabinoids.
Endocannabinoids – These are the compounds that keep the internal functions of the body running smoothly. All mammals produce endocannabinoids. By taking CBD, you supplement and enhance the functions.
Through non-cannabinoid receptors Serotonin receptors – At high concentrations, CBD activates specific serotonin receptors to confer its calming and relaxing effects.
Vanilloid receptors – CBD also interacts with the TRPV1 receptors, which also act as ion channels. These receptors help to mediate pain perception, body temperature and inflammation. By binding to the TRPV1 receptor, CBD is believed to influence pain perception.
Orphan receptors – CBD blocks or deactivates receptor called the GPR55 receptor, which is also called the orphan receptor. It’s found in the cerebellum and modulates bone density, blood pressure and other physiological processes. An overactive GPR55 receptor is often associated with conditions like osteoporosis. By blocking or deactivating this receptor, CBD can confer various benefits.
